Topic Overview
Respiratory Infections
1. Introduction
Definition
- Infectious diseases affecting the respiratory tract (upper or lower)
Key Concepts
Mode of Spread
- Airborne transmission
- Infection spreads via droplet nuclei (<5 µm)
- Remain suspended in air for long duration
- Travel long distances
- Droplet transmission
- Spread via respiratory droplets (>5 µm)
- Travel short distance (~1 meter)
- Settle quickly
Public Health Importance
- Major cause of:
- Morbidity (common infections like URTI, influenza)
- Mortality (pneumonia, TB, COVID-19)
- High transmission potential
- Especially in crowded settings
- Seasonal outbreaks common
🔥 Flowchart: Modes of Transmission (VERY IMPORTANT)
Respiratory Infection Transmission
│
├── Airborne
│ • Droplet nuclei (<5 µm)
│ • Long-distance spread
│ • Remains suspended
│ • Examples → TB, Measles
│
└── Droplet
• Larger droplets (>5 µm)
• Short-distance (~1 m)
• Settle quickly
• Examples → Influenza, COVID-19
🚀 Ultra High-Yield Points (NEET PG / MBBS)
- Airborne → long distance + suspended particles
- Droplet → short distance + heavy particles
- TB → classic airborne disease
- Measles → most infectious airborne disease
- Influenza → droplet spread
✅ Common Respiratory Infections ⭐
List of Important Diseases
- Tuberculosis (TB) ⭐
- Diphtheria ⭐
- Pertussis
- Measles ⭐
- Influenza
- COVID-19
🔥 Table: Disease vs Agent vs Transmission vs Vaccine (REVISION TABLE)
| Disease |
Causative Agent |
Mode of Transmission |
Vaccine |
| Tuberculosis (TB) |
Mycobacterium tuberculosis |
Airborne |
BCG |
| Diphtheria |
Corynebacterium diphtheriae |
Droplet |
DPT / Pentavalent |
| Pertussis |
Bordetella pertussis |
Droplet |
DPT / Pentavalent |
| Measles |
Measles virus |
Airborne |
MR / MMR |
| Influenza |
Influenza virus |
Droplet |
Influenza vaccine |
| COVID-19 |
SARS-CoV-2 |
Droplet / Airborne |
COVID-19 vaccines |
🚀 Ultra High-Yield Points (NEET PG / MBBS)
- TB & Measles → Airborne (very important MCQ)
- Diphtheria & Pertussis → Droplet spread
- BCG → TB prevention (partial protection)
- Pentavalent → Diphtheria + Pertussis + others
- COVID-19 → Mixed transmission (droplet + airborne)
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